CATH Domain 2e7aA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.120	Jelly Rolls
	2.60.120.40

Domain Context

CATH Clusters

Superfamily	2.60.120.40
Functional Family	Tumor necrosis factor

Enzyme Information

UniProtKB Entries (1)

TNFA_HUMAN

Homo sapiens

Tumor necrosis factor

PDB Structure

PDB	2E7A
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist Shibata, H., Yoshioka, Y., Ohkawa, A., Minowa, K., Mukai, Y., Abe, Y., Taniai, M., Nomura, T., Kayamuro, H., Nabeshi, H., Sugita, T., Imai, S., Nagano, K., Yoshikawa, T., Fujita, T., Nakagawa, S., Yamamoto, A., Ohta, T., Hayakawa, T., Mayumi, T., Vandenabeele, P., Aggarwal, B.B., Nakamura, T., Yamagata, Y., Tsunoda, S., Kamada, H., Tsutsumi, Y. J.Biol.Chem.