CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.950.10
Functional Family dITP/XTP pyrophosphatase

Enzyme Information

3.6.1.66
XTP/dITP diphosphatase.
based on mapping to UniProt O59580
(1) XTP + H(2)O = XMP + diphosphate. (2) dITP + H(2)O = dIMP + diphosphate. (3) ITP + H(2)O = IMP + diphosphate.
-!- The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP, dITP and ITP.

UniProtKB Entries (1)

O59580
IXTPA_PYRHO
Pyrococcus horikoshii OT3
DITP/XTP pyrophosphatase

PDB Structure

PDB 2E5X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of nucleotide triphosphate pyrophosphatase from pyrococcus horikoshii OT3
Mizutani, H., Lokanath, N.K., Kunishima, N.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...