CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Disintegrin and metalloproteinase domain-containing protein 22 |
Enzyme Information
| 3.4.24.58 |
Russellysin.
based on mapping to UniProt Q7LZ61
Specifically activates several components of the blood clotting system, including coagulation factor X, coagulation factor IX and protein C by cleavage of Arg-|-Xaa bonds. Has no action on insulin B chain.
-!- Belongs to peptidase family M12B.
|
UniProtKB Entries (1)
| Q4PRD2 |
SLLC2_DABSI
Daboia siamensis
Snaclec coagulation factor X-activating enzyme light chain 2
|
PDB Structure
| PDB | 2E3X |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of RVV-X: an example of evolutionary gain of specificity by ADAM proteinases.
Febs Lett.
|
