CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.60 | Phosphoenolpyruvate-binding domains |
Domain Context
CATH Clusters
| Superfamily | Phosphoenolpyruvate-binding domains |
| Functional Family | Phosphonopyruvate hydrolase |
Enzyme Information
| 3.11.1.3 |
Phosphonopyruvate hydrolase.
based on mapping to UniProt Q84G06
3-phosphonopyruvate + H(2)O = pyruvate + phosphate.
-!- Highly specific for phosphonopyruvate as substrate. -!- The reaction is not inhibited by phosphate but is inhibited by the phosphonates phosphonoformic acid, hydroxymethylphosphonic acid and 3-phosphonopropanoic acid.
|
UniProtKB Entries (1)
| Q84G06 |
PPHA_VARSP
Variovorax sp. Pal2
Phosphonopyruvate hydrolase
|
PDB Structure
| PDB | 2DUA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure and Kinetics of Phosphonopyruvate Hydrolase from Voriovorax sp. Pal2: New Insight into the Divergence of Catalysis within the PEP Mutase/Isocitrate Lyase Superfamily
Biochemistry
|