CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1820 | Ribonuclease H-like motif |
|
3.40.1820.10 | DnaQ-like 3'-5' exonuclease |
Domain Context
CATH Clusters
| Superfamily | DnaQ-like 3'-5' exonuclease |
| Functional Family | DNA-directed DNA polymerase |
Enzyme Information
| 2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q38087
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
| 3.1.11.- |
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q38087
|
UniProtKB Entries (1)
| Q38087 |
DPOL_BPR69
Enterobacteria phage RB69
DNA-directed DNA polymerase
|
PDB Structure
| PDB | 2DTU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family.
J.Biol.Chem.
|