CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.360 | Dihydrodipicolinate Reductase; domain 2 |
|
3.30.360.10 | Dihydrodipicolinate Reductase; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Dihydrodipicolinate Reductase; domain 2 |
| Functional Family |
Enzyme Information
| 1.4.1.21 |
Aspartate dehydrogenase.
based on mapping to UniProt O28440
L-aspartate + H(2)O + NAD(P)(+) = oxaloacetate + NH(3) + NAD(P)H.
-!- Catalyzes the first step in NAD biosynthesis from aspartate. -!- Strictly specific for L-aspartate as substrate. -!- Has a higher affinity for NAD(+) than NADP(+).
|
UniProtKB Entries (1)
| O28440 |
ASPD_ARCFU
Archaeoglobus fulgidus DSM 4304
Probable L-aspartate dehydrogenase
|
PDB Structure
| PDB | 2DC1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of archaeal highly thermostable L-aspartate dehydrogenase/NAD/citrate ternary complex.
Febs J.
|
