CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.80 | Trefoil |
|
2.80.10 | Trefoil (Acidic Fibroblast Growth Factor, subunit A) |
|
2.80.10.50 |
Domain Context
CATH Clusters
| Superfamily | 2.80.10.50 |
| Functional Family | Polypeptide N-acetylgalactosaminyltransferase |
Enzyme Information
| 2.4.1.41 |
Polypeptide N-acetylgalactosaminyltransferase.
based on mapping to UniProt Q86SR1
(1) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine. (2) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine.
-!- The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, kappa-casein, apofetuin and some other acceptors of high molecular mass.
|
UniProtKB Entries (1)
| Q86SR1 |
GLT10_HUMAN
Homo sapiens
Polypeptide N-acetylgalactosaminyltransferase 10
|
PDB Structure
| PDB | 2D7R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Pichia |
| Primary Citation |
Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10)
J.Mol.Biol.
|
