CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.190 | D-Maltodextrin-Binding Protein; domain 2 |
|
3.40.190.80 |
Domain Context
CATH Clusters
| Superfamily | 3.40.190.80 |
| Functional Family | Inositol-1-monophosphatase |
Enzyme Information
| 3.1.3.25 |
Inositol-phosphate phosphatase.
based on mapping to UniProt O14732
Myo-inositol phosphate + H(2)O = myo-inositol + phosphate.
-!- Acts on five of the six isomers of myo-inositol phosphate, all except myo-inositol 2-phosphate, but does not act on myo-inositol bearing more than one phosphate group. -!- It also acts on adenosine 2'-phosphate (but not the 3'- or 5'-phosphates), sn-glycerol 3-phosphate and glycerol 2-phosphate, but does not act on inositol bisphosphates or more phosphorylated inositols.
|
UniProtKB Entries (1)
| O14732 |
IMPA2_HUMAN
Homo sapiens
Inositol monophosphatase 2
|
PDB Structure
| PDB | 2CZK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures
Proteins
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