CATH Classification

Domain Context

CATH Clusters

Superfamily ACP-like
Functional Family 10-formyltetrahydrofolate dehydrogenase

Enzyme Information

1.5.1.6
Formyltetrahydrofolate dehydrogenase.
based on mapping to UniProt O75891
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.

UniProtKB Entries (1)

O75891
AL1L1_HUMAN
Homo sapiens
Cytosolic 10-formyltetrahydrofolate dehydrogenase

PDB Structure

PDB 2CQ8
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of RSGI RUH-033, a pp-binding domain of 10-FTHFDH from human cDNA
Abe, T., Hirota, H., Hayashi, F., Yokoyama, S.
To be Published
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