CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Adenylate kinase 1 |
Enzyme Information
| 2.7.4.3 |
Adenylate kinase.
based on mapping to UniProt P00568
ATP + AMP = 2 ADP.
-!- Inorganic triphosphate can also act as donor.
|
| 2.7.4.6 |
Nucleoside-diphosphate kinase.
based on mapping to UniProt P00568
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
|
UniProtKB Entries (1)
| P00568 |
KAD1_HUMAN
Homo sapiens
Adenylate kinase isoenzyme 1
|
PDB Structure
| PDB | 2C95 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Adenylate Kinase 1 in Complex with P1, P4-Di(Adenosine)Tetraphosphate
To be Published
|