CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | 5-aminolevulinate synthase, mitochondrial |
Enzyme Information
| 2.3.1.37 |
5-aminolevulinate synthase.
based on mapping to UniProt P18079
Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2).
|
UniProtKB Entries (1)
| P18079 |
HEM1_RHOCB
Rhodobacter capsulatus SB 1003
5-aminolevulinate synthase
|
PDB Structure
| PDB | 2BWP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans.
Embo J.
|
