CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.25 | Methionyl-tRNA Fmet Formyltransferase; Chain A, domain 2 |
|
3.10.25.10 | Formyl transferase, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Formyl transferase, C-terminal domain |
| Functional Family |
Enzyme Information
| 1.1.1.305 |
UDP-glucuronic acid oxidase (UDP-4-keto-hexauronic acid decarboxylating).
based on mapping to UniProt P77398
UDP-alpha-D-glucuronate + NAD(+) = UDP-beta-L-threo-pentapyranos-4-ulose + CO(2) + NADH.
-!- The activity is part of a bifunctional enzyme also performing the reaction of EC 2.1.2.13. -!- Formerly EC 1.1.1.n1.
|
| 2.1.2.13 |
UDP-4-amino-4-deoxy-L-arabinose formyltransferase.
based on mapping to UniProt P77398
10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinose.
-!- The activity is part of a bifunctional enzyme also performing the reaction of EC 1.1.1.305. -!- Formerly EC 2.1.2.n1.
|
UniProtKB Entries (1)
| P77398 |
ARNA_ECOLI
Escherichia coli K-12
Bifunctional polymyxin resistance protein ArnA
|
PDB Structure
| PDB | 2BLN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure and Function of Both Domains of Arna, a Dual Function Decarboxylase and a Formyltransferase, Involved in 4-Amino-4-Deoxy-L-Arabinose Biosynthesis.
J.Biol.Chem.
|
