CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Short-chain dehydrogenase reductase |
Enzyme Information
| 1.1.1.331 |
Secoisolariciresinol dehydrogenase.
based on mapping to UniProt Q94KL8
(-)-secoisolariciresinol + 2 NAD(+) = (-)-matairesinol + 2 NADH.
-!- Isolated from the plants Forsythia intermedia and Podophyllum peltatum. -!- An intermediate lactol is detected in vitro.
|
UniProtKB Entries (1)
| Q94KL8 |
SILD_PODPE
Podophyllum peltatum
Secoisolariciresinol dehydrogenase
|
PDB Structure
| PDB | 2BGM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of Apo-Form and Binary/Ternary Complexes of Podophyllum Secoisolariciresinol Dehydrogenase, an Enzyme Involved in Formation of Health-Protecting and Plant Defense Lignans
J.Biol.Chem.
|
