CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.60 | 4-Layer Sandwich |
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3.60.15 | Metallo-beta-lactamase; Chain A |
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3.60.15.10 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Domain Context
CATH Clusters
Superfamily | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Functional Family |
Enzyme Information
3.5.2.6 |
Beta-lactamase.
based on mapping to UniProt P04190
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.
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UniProtKB Entries (1)
P04190 |
BLA2_BACCE
Bacillus cereus
Metallo-beta-lactamase type 2
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PDB Structure
PDB | 2BG6 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry
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