CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.30 | Gcn5-related N-acetyltransferase (GNAT) |
Domain Context
CATH Clusters
| Superfamily | 3.40.630.30 |
| Functional Family | Diamine acetyltransferase 1 |
Enzyme Information
| 2.3.1.57 |
Diamine N-acetyltransferase.
based on mapping to UniProt P21673
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
-!- Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)- acetylspermidine and N(8)-acetylspermidine.
|
UniProtKB Entries (1)
| P21673 |
SAT1_HUMAN
Homo sapiens
Diamine acetyltransferase 1
|
PDB Structure
| PDB | 2B5G |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target
Proc.Natl.Acad.Sci.Usa
|
