CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Short-chain dehydrogenase reductase

Enzyme Information

1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase.
based on mapping to UniProt Q9RPT1
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
-!- Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates.

UniProtKB Entries (1)

Q9RPT1
RHLG_PSEAE
Pseudomonas aeruginosa PAO1
Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase

PDB Structure

PDB 2B4Q
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of RhlG, an Essential beta-Ketoacyl Reductase in the Rhamnolipid Biosynthetic Pathway of Pseudomonas aeruginosa.
Miller, D.J., Zhang, Y.-M., Rock, C.O., White, S.W.
J.Biol.Chem.