CATH Classification

Domain Context

CATH Clusters

Superfamily C2 domain
Functional Family phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

Enzyme Information

2.7.1.154
Phosphatidylinositol-4-phosphate 3-kinase.
based on mapping to UniProt Q61194
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 3,4-bisphosphate.
-!- This enzyme also phosphorylates PtdIns to PtdIns3P.

UniProtKB Entries (1)

Q61194
P3C2A_MOUSE
Mus musculus
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

PDB Structure

PDB 2B3R
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2alpha.
Liu, L., Song, X., He, D., Komma, C., Kita, A., Virbasius, J.V., Huang, G., Bellamy, H.D., Miki, K., Czech, M.P., Zhou, G.W.
J.Biol.Chem.
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