CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family |
Enzyme Information
| 2.6.1.57 |
Aromatic-amino-acid transaminase.
based on mapping to UniProt P95468
An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.
-!- L-methionine can also act as donor, more slowly. -!- Oxaloacetate can act as acceptor. -!- Controlled proteolysis converts the enzyme to EC 2.6.1.1.
|
UniProtKB Entries (1)
| P95468 |
TYRB_PARDE
Paracoccus denitrificans
Aromatic-amino-acid aminotransferase
|
PDB Structure
| PDB | 2AY9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: flexibility and rigidity.
Biochemistry
|
