CATH Domain 2am2A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.10	Mur-like, catalytic domain

Domain Context

CATH Clusters

Superfamily	Mur-like, catalytic domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q8DNV6_STRR6

Streptococcus pneumoniae R6

UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

PDB Structure

PDB	2AM2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure Longenecker, K.L., Stamper, G.F., Hajduk, P.J., Fry, E.H., Jakob, C.G., Harlan, J.E., Edalji, R., Bartley, D.M., Walter, K.A., Solomon, L.R., Holzman, T.F., Gu, Y.G., Lerner, C.G., Beutel, B.A., Stoll, V.S. Protein Sci.