CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.80 | Acyl-CoA Binding Protein | |
1.20.80.10 |
Domain Context
CATH Clusters
Superfamily | 1.20.80.10 |
Functional Family | Protein-tyrosine kinase 2-beta isoform 1 |
Enzyme Information
2.7.10.2 |
Non-specific protein-tyrosine kinase.
based on mapping to UniProt Q00944
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
Q00944 |
FAK1_CHICK
Gallus gallus
Focal adhesion kinase 1
|
PDB Structure
PDB | 2AL6 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem.
|