CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.533 | Death Domain, Fas |
|
1.10.533.10 | Death Domain, Fas |
Domain Context
CATH Clusters
| Superfamily | Death Domain, Fas |
| Functional Family | Interleukin 1 receptor-associated kinase 4 |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q8R4K2
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
| Q8R4K2 |
IRAK4_MOUSE
Mus musculus
Interleukin-1 receptor-associated kinase 4
|
PDB Structure
| PDB | 2A9I |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Cutting Edge: Molecular Structure of the IL-1R-Associated Kinase-4 Death Domain and Its Implications for TLR Signaling.
J.Immunol.
|