CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.1740 | Rna Polymerase Sigma Factor; Chain: A |
|
1.10.1740.100 | Set2, Rpb1 interacting domain |
Domain Context
CATH Clusters
| Superfamily | Set2, Rpb1 interacting domain |
| Functional Family | Histone-lysine N-methyltransferase |
Enzyme Information
| 2.1.1.- |
Methyltransferases.
based on mapping to UniProt Q9BYW2
|
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9BYW2
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (1)
| Q9BYW2 |
SETD2_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD2
|
PDB Structure
| PDB | 2A7O |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Solution structure of the Set2 Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1
Proc.Natl.Acad.Sci.USA
|