CATH Domain 2a69F02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q5SKW1_THET8

Thermus thermophilus HB8

RNA polymerase sigma factor SigA

PDB Structure

PDB	2A69
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Artsimovitch, I., Vassylyeva, M.N., Svetlov, D., Svetlov, V., Perederina, A., Igarashi, N., Matsugaki, N., Wakatsuki, S., Tahirov, T.H., Vassylyev, D.G. Cell(Cambridge,Mass.)