CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q9Q2G8
Q9Q2G8_9HIV1
Human immunodeficiency virus 1
V-1 protease

PDB Structure

PDB 2A4F
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains
Zhao, C., Sham, H.L., Sun, M., Stoll, V.S., Stewart, K.D., Lin, S., Mo, H., Vasavanonda, S., Saldivar, A., Park, C., McDonald, E.J., Marsh, K.C., Klein, L.L., Kempf, D.J., Norbeck, D.W.
Bioorg.Med.Chem.Lett.