CATH Classification

Domain Context

CATH Clusters

Superfamily 5' to 3' exonuclease, C-terminal subdomain
Functional Family DNA repair endonuclease XPF isoform X2

Enzyme Information

3.1.-.-
Acting on ester bonds.
based on mapping to UniProt Q92889

UniProtKB Entries (1)

Q92889
XPF_HUMAN
Homo sapiens
DNA repair endonuclease XPF

PDB Structure

PDB 2A1J
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1.
Tsodikov, O.V., Enzlin, J.H., Scharer, O.D., Ellenberger, T.
Proc.Natl.Acad.Sci.Usa
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