CATH Domain 1zyiA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	methylosome subunit pICln isoform X1

Enzyme Information

UniProtKB Entries (1)

ICLN_CANLF

Canis lupus familiaris

Methylosome subunit pICln

PDB Structure

PDB	1ZYI
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4 Schedlbauer, A., Gandini, R., Garavaglia, M.L., Saino, S., Gschwentner, M., Sarg, B., Lindner, H., Jakab, M., Ritter, M., Bazzini, C., Botta, G., Meyer, G., Kontaxis, G., Tilly, B.C., Konrat, R., Paulmichl, M. J.Biol.Chem.