CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.200 | Phosphorylase Kinase; domain 1 | |
3.30.200.20 | Phosphorylase Kinase; domain 1 |
Domain Context
CATH Clusters
Superfamily | Phosphorylase Kinase; domain 1 |
Functional Family | eIF-2-alpha kinase GCN2 |
Enzyme Information
2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P15442
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
P15442 |
GCN2_YEAST
Saccharomyces cerevisiae S288C
EIF-2-alpha kinase GCN2
|
PDB Structure
PDB | 1ZY4 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structural Basis for Autoinhibition and Mutational Activation of Eukaryotic Initiation Factor 2{alpha} Protein Kinase GCN2
J.Biol.Chem.
|