CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.10 | Thrombin, subunit H | |
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
Superfamily | Trypsin-like serine proteases |
Functional Family | Coagulation factor XI |
Enzyme Information
3.4.21.27 |
Coagulation factor XIa.
based on mapping to UniProt P03951
Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form factor IXa.
-!- The proenzyme XI is activated by EC 3.4.21.38. -!- Belongs to peptidase family S1.
|
UniProtKB Entries (1)
P03951 |
FA11_HUMAN
Homo sapiens
Coagulation factor XI
|
PDB Structure
PDB | 1ZPZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Pichia |
Primary Citation |
Design, Synthesis and Biological Evaluation of Peptidomimetic FXIa Inhibitors
To be Published
|