CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.70 | Cathepsin D, subunit A; domain 1 |
|
2.40.70.10 | Acid Proteases |
Domain Context
CATH Clusters
| Superfamily | Acid Proteases |
| Functional Family | Gag-Pol polyprotein |
Enzyme Information
UniProtKB Entries (2)
| P03367 |
POL_HV1BR
Human immunodeficiency virus type 1 (BRU ISOLATE)
Gag-Pol polyprotein
|
| Q7ZCL6 |
Q7ZCL6_9HIV1
Human immunodeficiency virus 1
Protease
|
PDB Structure
| PDB | 1ZLF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
HIV-1 protease mutations and inhibitor modifications monitored on a series of complexes. Structural basis for the effect of the A71V mutation on the active site
J.Med.Chem.
|
