CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1240 | Zincin-like |
|
3.90.1240.10 | Metalloproteases ("zincins"), catalytic domain like |
Domain Context
CATH Clusters
| Superfamily | Metalloproteases ("zincins"), catalytic domain like |
| Functional Family | Botulinum neurotoxin type B |
Enzyme Information
| 3.4.24.69 |
Bontoxilysin.
based on mapping to UniProt Q00496
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.
|
UniProtKB Entries (1)
| Q00496 |
BXE_CLOBO
Clostridium botulinum
Botulinum neurotoxin type E
|
PDB Structure
| PDB | 1ZKX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry
|
