CATH Domain 1zj2A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
	3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family	Histo-blood group ABO system transferase

Enzyme Information

2.4.1.37

Fucosylgalactoside 3-alpha-galactosyltransferase.

based on mapping to UniProt P16442

UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP + alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.

-!- Acts on blood group substance, and can use a number of 2-fucosyl- galactosides as acceptors.

2.4.1.40

Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase.

based on mapping to UniProt P16442

UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl- (1->2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl- (1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactose.

-!- Acts on blood group substance H. -!- Can use a number of 2-fucosyl-galactosides as acceptors.

UniProtKB Entries (1)

P16442

BGAT_HUMAN

Homo sapiens

Histo-blood group ABO system transferase

PDB Structure

PDB	1ZJ2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. Letts, J.A., Rose, N.L., Fang, Y.R., Barry, C.H., Borisova, S.N., Seto, N.O., Palcic, M.M., Evans, S.V. J.Biol.Chem.