CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.50 | 3-Layer(bba) Sandwich | |
3.50.50 | FAD/NAD(P)-binding domain | |
3.50.50.60 | FAD/NAD(P)-binding domain |
Domain Context
CATH Clusters
Superfamily | FAD/NAD(P)-binding domain |
Functional Family | Thioredoxin reductase 2, mitochondrial |
Enzyme Information
1.8.1.9 |
Thioredoxin-disulfide reductase.
based on mapping to UniProt Q9JLT4
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.
|
UniProtKB Entries (1)
Q9JLT4 |
TRXR2_MOUSE
Mus musculus
Thioredoxin reductase 2, mitochondrial
|
PDB Structure
PDB | 1ZDL |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism.
Proc.Natl.Acad.Sci.Usa
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