CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.170 | Beta Complex | |
2.170.16 | Endonuclease - Pi-scei; Chain A, domain 1 | |
2.170.16.10 | Hedgehog/Intein (Hint) domain |
Domain Context
CATH Clusters
Superfamily | Hedgehog/Intein (Hint) domain |
Functional Family |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P74750
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
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UniProtKB Entries (1)
P74750 |
DPO3A_SYNY3
Synechocystis sp. PCC 6803 substr. Kazusa
DNA polymerase III subunit alpha
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PDB Structure
PDB | 1ZDE |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing
J.Mol.Biol.
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