CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family MTA/SAH nucleosidase family protein

Enzyme Information

3.2.2.9
Adenosylhomocysteine nucleosidase.
based on mapping to UniProt P0AF12
S-adenosyl-L-homocysteine + H(2)O = S-(5-deoxy-D-ribos-5-yl)-L- homocysteine + adenine.

UniProtKB Entries (1)

P0AF12
MTNN_ECOLI
Escherichia coli K-12
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

PDB Structure

PDB 1Z5O
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis
Lee, J.E., Smith, G.D., Horvatin, C., Huang, D.J.T., Cornell, K.A., Riscoe, M.K., Howell, P.L.
J.Mol.Biol.
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