CATH Classification

Domain Context

CATH Clusters

Superfamily Metalloproteases ("zincins"), catalytic domain like
Functional Family Botulinum neurotoxin type B

Enzyme Information

3.4.24.68
Tentoxilysin.
based on mapping to UniProt P04958
Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P04958
TETX_CLOTE
Clostridium tetani E88
Tetanus toxin

PDB Structure

PDB 1YVG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural analysis of the catalytic domain of tetanus neurotoxin.
Rao, K.N., Kumaran, D., Binz, T., Swaminathan, S.
Toxicon
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