CATH Domain 1ysiA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.437	Apoptosis Regulator Bcl-x
	1.10.437.10	Blc2-like

Domain Context

CATH Clusters

Superfamily	Blc2-like
Functional Family	Bcl-2-like protein 1

Enzyme Information

UniProtKB Entries (1)

B2CL1_HUMAN

Homo sapiens

Bcl-2-like protein 1

PDB Structure

PDB	1YSI
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	An inhibitor of Bcl-2 family proteins induces regression of solid tumours Oltersdorf, T., Elmore, S.W., Shoemaker, A.R., Armstrong, R.C., Augeri, D.J., Belli, B.A., Bruncko, M., Deckwerth, T.L., Dinges, J., Hajduk, P.J., Joseph, M.K., Kitada, S., Korsmeyer, S.J., Kunzer, A.R., Letai, A., Li, C., Mitten, M.J., Nettesheim, D.G., Ng, S., Nimmer, P.M., O'Connor, J.M., Oleksijew, A., Petros, A.M., Reed, J.C., Shen, W., Tahir, S.K., Thompson, C.B., Tomaselli, K.J., Wang, B., Wendt, M.D., Zhang, H., Fesik, S.W., Rosenberg, S.H. Nature