CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.109 | NADH Oxidase |
|
3.40.109.10 | NADH Oxidase |
Domain Context
CATH Clusters
| Superfamily | NADH Oxidase |
| Functional Family | Oxygen-insensitive NAD(P)H nitroreductase |
Enzyme Information
| 1.5.1.34 |
6,7-dihydropteridine reductase.
based on mapping to UniProt P38489
A 5,6,7,8-tetrahydropteridine + NAD(P)(+) = a 6,7-dihydropteridine + NAD(P)H.
-!- The substrate is the quinonoid form of dihydropteridine. -!- Not identical with EC 1.5.1.3. -!- Formerly EC 1.6.99.7 and EC 1.6.99.10.
|
| 1.-.-.- |
Oxidoreductases.
based on mapping to UniProt P38489
|
UniProtKB Entries (1)
| P38489 |
NFSB_ECOLI
Escherichia coli K-12
Oxygen-insensitive NAD(P)H nitroreductase
|
PDB Structure
| PDB | 1YLR |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem.
|
