CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Hydroxymethylglutaryl-CoA lyase |
Enzyme Information
UniProtKB Entries (1)
| Q8YEF2 |
Q8YEF2_BRUME
Brucella melitensis bv. 1 str. 16M
Hydroxymethylglutaryl-CoA lyase
|
PDB Structure
| PDB | 1YDN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.
J.Biol.Chem.
|
