CATH Classification

Domain Context

CATH Clusters

Superfamily Formaldehyde-activating enzyme
Functional Family 5,6,7,8-tetrahydromethanopterin hydro-lyase

Enzyme Information

4.2.1.147
5,6,7,8-tetrahydromethanopterin hydro-lyase.
based on mapping to UniProt Q9FA38
5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10- methylenetetrahydromethanopterin + H(2)O.
-!- Found in methylotrophic bacteria and methanogenic archaea.

UniProtKB Entries (1)

Q9FA38
FAE_METEA
Methylorubrum extorquens AM1
5,6,7,8-tetrahydromethanopterin hydro-lyase

PDB Structure

PDB 1Y60
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
How an enzyme binds the C1-carrier tetrahydromethanopterin: Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1
Acharya, P., Goenrich, M., Hagemeier, C.H., Demmer, U., Vorholt, J.A., Thauer, R.K., Ermler, U.
J.Biol.Chem.