CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10540 | Crotonobetainyl-coa:carnitine coa-transferase; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Crotonobetainyl-coa:carnitine coa-transferase; domain 1 |
| Functional Family | L-carnitine CoA-transferase |
Enzyme Information
| 2.8.3.21 |
L-carnitine CoA-transferase.
based on mapping to UniProt P31572
(1) (E)-4-(trimethylammonio)but-2-enoyl-CoA + L-carnitine = (E)-4- (trimethylammonio)but-2-enoate + L-carnitinyl-CoA. (2) 4-trimethylammoniobutanoyl-CoA + L-carnitine = 4-trimethylammoniobutanoate + L-carnitinyl-CoA.
-!- The enzyme is found in gammaproteobacteria such as Proteus sp. and Escherichia coli. -!- It has similar activity with both substrates. -!- Formerly EC 4.2.1.89.
|
UniProtKB Entries (1)
| P31572 |
CAIB_ECOLI
Escherichia coli K-12
L-carnitine CoA-transferase
|
PDB Structure
| PDB | 1XVV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Escherichia coli Crotonobetainyl-CoA: Carnitine CoA-Transferase (CaiB) and Its Complexes with CoA and Carnitinyl-CoA.
Biochemistry
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