1 keywords

CATH Domain 1xpcA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Estrogen receptor

Enzyme Information

UniProtKB Entries (1)

P03372
ESR1_HUMAN
Homo sapiens
Estrogen receptor

PDB Structure

PDB 1XPC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Blizzard, T.A., Dininno, F., Morgan, J.D., Chen, H.Y., Wu, J.Y., Kim, S., Chan, W., Birzin, E.T., Yang, Y.T., Pai, L.Y., Fitzgerald, P.M., Sharma, N., Li, Y., Zhang, Z., Hayes, E.C., Dasilva, C.A., Tang, W., Rohrer, S.P., Schaeffer, J.M., Hammond, M.L.
Bioorg.Med.Chem.Lett.