CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.460 | ppGaNTase-T1 linker domain-like |
Domain Context
CATH Clusters
| Superfamily | ppGaNTase-T1 linker domain-like |
| Functional Family | Polypeptide N-acetylgalactosaminyltransferase |
Enzyme Information
| 2.4.1.41 |
Polypeptide N-acetylgalactosaminyltransferase.
based on mapping to UniProt O08912
(1) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-serine. (2) UDP-N-acetyl-alpha-D-galactosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-alpha-D-galactosaminyl)-L-threonine.
-!- The glycosyl residue is transferred to threonine or serine hydroxy groups on the polypeptide core of submaxillary mucin, kappa-casein, apofetuin and some other acceptors of high molecular mass.
|
UniProtKB Entries (1)
| O08912 |
GALT1_MOUSE
Mus musculus
Polypeptide N-acetylgalactosaminyltransferase 1
|
PDB Structure
| PDB | 1XHB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Pichia |
| Primary Citation |
The beginnings of mucin biosynthesis: The crystal structure of UDP-GalNAc:polypeptide {alpha}-N-acetylgalactosaminyltransferase-T1
Proc.Natl.Acad.Sci.USA
|
