CATH Classification
Domain Context
CATH Clusters
| Superfamily | glutathione-dependent formaldehyde- activating enzyme (gfa) |
| Functional Family |
Enzyme Information
| 4.4.1.22 |
S-(hydroxymethyl)glutathione synthase.
based on mapping to UniProt Q51669
S-(hydroxymethyl)glutathione = glutathione + formaldehyde.
-!- The enzyme from Paracoccus denitrificans accelerates the spontaneous reaction in which the adduct of formaldehyde and glutathione is formed, i.e. the substrate for EC 1.1.1.284, in the formaldehyde- detoxification pathway. -!- Formerly EC 1.2.1.1.
|
UniProtKB Entries (1)
| Q51669 |
GFA_PARDE
Paracoccus denitrificans
Glutathione-dependent formaldehyde-activating enzyme
|
PDB Structure
| PDB | 1XA8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
A dynamic zinc redox switch
J.Biol.Chem.
|