CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | Rho guanine nucleotide exchange factor 1 |
Enzyme Information
UniProtKB Entries (1)
| Q9NZN5 |
ARHGC_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 12
|
PDB Structure
| PDB | 1X86 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem.
|
