CATH Classification

Domain Context

CATH Clusters

Superfamily Dbl homology (DH) domain
Functional Family Rho guanine nucleotide exchange factor (GEF) 11

Enzyme Information

UniProtKB Entries (1)

P61586
RHOA_HUMAN
Homo sapiens
Transforming protein RhoA

PDB Structure

PDB 1X86
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
Kristelly, R., Gao, G., Tesmer, J.J.
J.Biol.Chem.
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