CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.230.10
Functional Family Galactokinase 1

Enzyme Information

2.7.1.6
Galactokinase.
based on mapping to UniProt P51570
ATP + alpha-D-galactose = ADP + alpha-D-galactose 1-phosphate.
-!- Part of the Leloir pathway for galactose metabolism. -!- The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine.

UniProtKB Entries (1)

P51570
GALK1_HUMAN
Homo sapiens
Galactokinase

PDB Structure

PDB 1WUU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Molecular Structure of Human Galactokinase: IMPLICATIONS FOR TYPE II GALACTOSEMIA
Thoden, J.B., Timson, D.J., Reece, R.J., Holden, H.M.
J.Biol.Chem.