CATH Domain 1wszA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
	3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family	Histo-blood group ABO system transferase

Enzyme Information

2.4.1.37

Fucosylgalactoside 3-alpha-galactosyltransferase.

based on mapping to UniProt P16442

UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = UDP + alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.

-!- Acts on blood group substance, and can use a number of 2-fucosyl- galactosides as acceptors.

2.4.1.40

Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase.

based on mapping to UniProt P16442

UDP-N-acetyl-alpha-beta-D-galactosamine + glycoprotein-alpha-L-fucosyl- (1->2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl- (1->3)-(alpha-L-fucosyl-(1->2))-beta-D-galactose.

-!- Acts on blood group substance H. -!- Can use a number of 2-fucosyl-galactosides as acceptors.

UniProtKB Entries (1)

P16442

BGAT_HUMAN

Homo sapiens

Histo-blood group ABO system transferase

PDB Structure

PDB	1WSZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural basis for the inactivity of human blood group o2 glycosyltransferase Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M. J.Biol.Chem.