CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.390 | Collagenase (Catalytic Domain) |
|
3.40.390.10 | Collagenase (Catalytic Domain) |
Domain Context
CATH Clusters
| Superfamily | Collagenase (Catalytic Domain) |
| Functional Family | Disintegrin and metalloproteinase domain-containing protein 22 |
Enzyme Information
| 3.4.24.53 |
Trimerelysin II.
based on mapping to UniProt P20165
Cleavage of 3-Asn-|-Gln-4, 10-His-|-Leu-11 and 14-Ala-|-Leu-15 in the insulin B chain, and the bond Z-Gly-Pro-|-Leu-Gly-Pro in a small molecule substrate of microbial collagenase.
-!- Nonhemorrhagic endopeptidase from the venom of the habu snake (Trimeresurus flavoviridis). -!- Belongs to peptidase family M12B.
|
UniProtKB Entries (1)
| P20165 |
VM1T2_PROFL
Protobothrops flavoviridis
Snake venom metalloproteinase trimerelysin-2
|
PDB Structure
| PDB | 1WNI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of H2-proteinase from the venom of Trimeresurus flavoviridis.
J.Biochem.
|
