CATH Classification

Domain Context

CATH Clusters

Superfamily Protein-arginine deiminase, central domain
Functional Family Protein-arginine deiminase type-2

Enzyme Information

3.5.3.15
Protein-arginine deiminase.
based on mapping to UniProt Q9UM07
Protein L-arginine + H(2)O = protein L-citrulline + NH(3).
-!- Also acts on N-acyl-L-arginine and, more slowly, on L-arginine esters.

UniProtKB Entries (1)

Q9UM07
PADI4_HUMAN
Homo sapiens
Protein-arginine deiminase type-4

PDB Structure

PDB 1WD9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for Ca(2+)-induced activation of human PAD4
Arita, K., Hashimoto, H., Shimizu, T., Nakashima, K., Yamada, M., Sato, M.
Nat.Struct.Mol.Biol.
CATH-Gene3D is a Global Biodata Core Resource Learn more...