CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.330 | B-lactam Antibiotic, Isopenicillin N Synthase; Chain |
Domain Context
CATH Clusters
| Superfamily | B-lactam Antibiotic, Isopenicillin N Synthase; Chain |
| Functional Family |
Enzyme Information
| 1.14.20.1 |
Deacetoxycephalosporin-C synthase.
based on mapping to UniProt P18548
Penicillin N + 2-oxoglutarate + O(2) = deacetoxycephalosporin C + succinate + CO(2) + H(2)O.
-!- Forms part of the penicillin biosynthesis pathway.
|
UniProtKB Entries (1)
| P18548 |
CEFE_STRC2
Streptomyces clavuligerus ATCC 27064
Deacetoxycephalosporin C synthase
|
PDB Structure
| PDB | 1W2N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Conformational Flexibility of the C Terminus with Implications for Substrate Binding and Catalysis Revealed in a New Crystal Form of Deacetoxycephalosporin C Synthase
J.Mol.Biol.
|
